Mad Honey In Your Diet: Pros & Cons

Mad Honey In Your Diet

July 26th, 2022   |   Updated on January 23rd, 2023

Mad honey, also known as grayanotoxin honey, is a type of honey that contains grayanotoxins. Bees that feed on the nectar of certain plants that contain grayanotoxins produce it.

It has been proven to be beneficial in some cases, but it can also be dangerous if consumed in large quantities. Below are some of the health benefits that mad honey can offer, as well as some risks to consider.


Lower Blood Pressure

The main benefit of mad honey is that it can help lower blood pressure. Grayanotoxins interact with voltage-gated sodium channels in the body, which helps to regulate blood pressure.

This improves circulation and can prevent hypertension. In one study, mad honey was shown to reduce blood pressure by up to 20% in people with hypertension.

Reduce Inflammation

Mad honey can also help to reduce inflammation. Grayanotoxins interact with voltage-gated calcium channels, which helps to reduce the release of inflammatory substances from cells.

In one study, mad honey was shown to reduce inflammation by up to 50%. This can help to relieve pain and swelling associated with conditions like arthritis which can lead to a better quality of life.

Aids In Digestion

Mad honey can also help aid digestion. Grayanotoxins help to stimulate smooth muscle contractions, which can help move food through the digestive tract.

This can relieve constipation and other digestive issues. It also helps to increase the production of digestive enzymes, which can improve the digestion of food.

Boosts Energy Levels

Another benefit of mad honey is that it can help to boost energy levels. Grayanotoxins interact with the mitochondria, which are the powerhouses of cells.

This helps to increase the production of ATP, which is used for energy. Mad honey has been shown to improve exercise performance and increase stamina.

Anti-Cancer Properties

Mad honey also has anti-cancer properties. Grayanotoxins can induce apoptosis, or cell death, in cancer cells. In one study, mad honey was shown to kill up to 95% of cancer cells in vitro.

The cells that were not killed underwent cell cycle arrest, which means they stopped growing and dividing. This suggests that mad honey could potentially be used as a treatment for cancer.

Antibacterial And Antifungal

Mad honey has been used for centuries in folk medicine as a treatment for various ailments. It has been shown to have antibacterial and antifungal properties.

In one study, mad honey was shown to be effective against a variety of bacteria, including Staphylococcus aureus and Escherichia coli which are common causes of infections. Mad honey can also help to treat fungal infections, such as Candida albicans.


Allergic Reactions

One of the most common side effects of mad honey is an allergic reaction. This is because the grayanotoxins in this honey can interact with the body’s immune system, causing it to overreact.

Allergic reactions can range from mild to severe, and in some cases, they can be life-threatening. If you are allergic to bee stings, you should avoid mad honey.

Symptoms of an allergic reaction include skin rashes, hives, swelling, and difficulty breathing. If you experience any of these symptoms after consuming mad honey, it is essential to seek medical help immediately.


Mad honey can also cause diarrhea. Grayanotoxins interact with the intestine. The intestine is responsible for absorbing water from the food we eat.

When grayanotoxins interfere with this process, it can lead to watery and loose stools. In one study, mad honey was shown to cause diarrhea in up to 50% of people who consumed it. However, this is usually only a problem if you consume large quantities of mad honey.


Mad honey that makes you high can also cause intoxication if consumed in large quantities. Grayanotoxins interact with the nervous system, which can lead to symptoms such as dizziness, nausea, and vomiting. In one study, mad honey was shown to cause intoxication in up to 20% of people who consumed it.

The grayanotoxins can also interact with the heart, which can lead to arrhythmias and cardiac arrest. In one study, mad honey was shown to be lethal in up to 50% of cases.

Pregnancy And Breastfeeding

Mad honey should not be consumed by pregnant or breastfeeding women as it can cause an allergic reaction in the baby. If you are pregnant or breastfeeding, it is essential to avoid mad honey.

Bottom Line

If you’re considering adding mad honey to your diet, it’s essential to speak with your healthcare provider first to weigh the potential risks and benefits.

Additionally, be sure to purchase mad honey from a reputable source to avoid any adulteration or contamination.


Health Disclaimer :

Information provided by does in no way substitute for a qualified medical opinion. Any text, videos, or any other material provided by us should be considered general information only. Any health-related information may vary from person to person, hence we advise you to consult specialists for more information.